Which Southern state has the most liberal Republicans?

[100% pro-life no matter what]

By politicians, maybe South Carolina.  It had a shockingly hard time even passing a heartbeat bill, when most comparable Southern states passed total bans without much issue (although, I should say that North Carolina settled for a nearly pointless 12 weeks).

For the actual voters, probably Florida if you call it the South.  It lacks the religious social conservatism seen in the rest of the South.  In many ways, Georgia would still feel way more conservative than Florida despite their modern partisan margins.