Looking a bit more deeply at the language of the redistricting measure, it seems to be designed not just to allow Republicans to keep gerrymandering (eg the fact that cross-cutting is only allowed between Cuyahoga and Summit makes me think they might keep OH-11's arm into Akron) but also to make Democratic gerrymanders more difficult.
Obviously it's deeply deeply unlikely that either the Ohio House or the Senate will flip (and if they do it's probably because Biden makes big inroads in demographics Democrats bombed with in 2016, making any scheme now less than useful.) But just for the sake of argument I tried to draw a gerrymander and found that both the requirement to keep Cleveland whole and the ban on cross-cuts makes drawing Democratic districts more difficult. The former hurts because it means that OH-11 has to take in too many white Democrats in west Cleveland to take significant numbers of white Republicans in NE Ohio, the latter because it's harder to grab blue cities without also having to take their ruby-red suburbs.
This was the best I could manage:
https://davesredistricting.org/join/ef954867-1844-405b-b0d4-1a7fd34a663c9 districts have Democratic PVIs, but only two are wave-proof and three are realistically swing rather than Democratic seats. Columbus is chopped three ways and whilst OH-15 definitely takes the bulk of it, it's questionable whether you'd get away with splitting the remainder between two different seats. Undoing that probably makes OH-12 safer for Dems, but at the cost of OH-3 getting more Republican.
OH-1: D+4.28
OH-2: R+20.12
OH-3: D+2.43
OH-4: R+12.67
OH-5: R+21.07
OH-6: R+14.65
OH-7: R+13.41
OH-8: R+18.97
OH-9: D+4.45
OH-10: D+1.44
OH-11: D+25.92 (44.2% black by CVAP)
OH-12: D+1.95
OH-13: D+4.31
OH-14: D+3.05
OH-15: D+8.31 (26.2% black by CVAP)