Women in the 16th century. Without them the world would be so different

[MissCatholic]

Cant thing of any women outisde the uk?

[12th Doctor]

Ummmm... there was Catherine of France as well... was it Catherine DeMenici?  Can't remember.  Isabella of Spain is another one.

[MissCatholic]

What did they do, any have such an impact not only on european history but also ours?

[Beet]

It's hard to imagine you left out Catherine de Medici of the powerful Medici family of Italy. Remember this was during the High Renaissance when the center of European civilization was still in the South and the Renaissance was gradually spreading northward, she Catherine's marriage was part of this.

Catherine enforced a ban on thick waists at the French court and set off a trend for nearly 350 years, where women's primary means of support was the corset, with laces and stays shrinking their waists.

On the death of Francis II in 1560, Catherine became regent during the minority of her second son, Charles IX of France. She was involved in the infamous St. Bartholomew's Day Massacre in 1572.

[Erc]

Catherine de Medici, obviously...

Marie de Medici (in the last ten years, and she isn't important anyway)...

There are probably a couple Italians...

There's Queen Juana the Mad of Castille...but, for obvious reasons, she had very little impact on history.

[Emsworth]

My vote goes to Elizabeth I; she had a great impact not only on England, but also on the rest of Europe: not her involvement in the Reformation, the Dutch rebellion, the Desmond rebellions, the Wars of Religion in France, the Anglo-Spanish War, etc.

Isabella of Castile and Catherine de Médicis were also significant figures, though, I would argue, not as much as Elizabeth.