Places that are reliably conservative/liberal except for 1-2 issues

[nclib]

Jersey Shore - conservative except support gun control
South Fla. Cubans - conservative except on English language issues
Amish areas - conservative except for pacifism

African-American areas - liberal except for gay rights (though of course would not interfere with their Democratic voting habits)

any others come to mind...

[freepcrusher]

lower OC for the most part is conservative in registration and voting except on what I call "below the belt" issues.

[tallguy23]

Having spent a lot of time in Orange County, it's no doubt the most conservative area in Southern California. However, I think it's conservatism is more rooted in economics and law & order issues. Socially the area is much more moderate. They voted for Prop 8 but seem to be fairly liberal on abortion. Even on gay marriage, OC seems to be shifting. The last time I was there I was shocked at the number of gay clubs opening up.

[Snowstalker Mk. II]

Blacks are trending more liberal on same-sex marriage based on polling (likely the NAACP endorsement and Barack Obama's endorsement has it gaining support as a civil rights issue).

West Virginia is an interesting hodgepodge--pro-union and supportive of a lot of state funding and aid, but the issues of coal, gun control, and same-sex marriage swing them to the GOP on a presidential level.