Is the cartoonist suggesting that Republicans need to support amnesty, abortion, gun control, tax increases, and compromise with Democrats to win elections?
The cartoon references the 1980 election. By that time, Reagan was pro-life and tax cuts were the central issue of his campaign. Immigration was a non-issue, and Reagan was the most pro-gun candidate in the election.
And yet he signed tax increases into law and gave amnesty to illegal immigrants.
That suggests that Tea Party ideas and rhetoric might win elections but are wholly useless and unworkable once you're sworn in and have to actually, you know, govern.