He's going to be a lameduck from day one, he's not going get his prefered cabinet picks, he's not going to get anything done with a narrow house majority and a 52-48 R majority in the senate, no court packings, no DC/PR Statehood. The Supreme Court is 6-3 conservative, they're going to dismantle the ACA, also the Democrats are going to get slaughtered in 2022/off-year elections.
Considering that healthcare has been the best issue for the Democrats in the last two elections, nothing could be more welcome to the Democratic party than a confirmation of their oft-repeated claim that "Republicans want to take away your healthcare" and use this to moblize outrage in a massive victory in 2024.