As in, Cory Gardner or Marco Rubio suddenly resigning out of nowhere? I guess that's a possibility. I'll go with 60% since, while I think it's POSSIBLE that Democrats will get one of UT/TX/NE/MS/WY/TN, it's unlikely that Democrats will do that while still retaining all current seats and picking up NV and AZ.
Not to be too morbid about it, but I think John McCain or Chuck Grassley dying suddenly is the more probable outcome.
Also, I could definitely see Collins flipping in a 50/50 Senate if she's fed up enough with Trump.