Considering how Huckabee handled the Republican Primaries (aka "not running for President) I severely doubt he would "go rogue". Like someone else on here mentioned, he had ample opportunity to stand up to the "establishment" and he did nothing. He decided that high cable ratings was more important than going against the Rombot. Huckabee is merely saying what he said to drum up the necessary fifteen minutes of fame to get more ratings for the next few months during elections season. At the very best he will tease the audience with possibilities and crazy scenarios, but he won't leave. As much as Republicans truly despise each other they won't turn their backs on the national ticket whole hog when the Kenyan Muslim Socialist Atheist is still president.
As it regards Akin I would expect some blowback, but nothing that would exceed the usual "THAT'S NOT FAIR!" criticism from the 10% who aren't overjoyed with the decision. Oh, and the liberals who WANT Akin to stay in the race, naturally. Now it's just a waiting game of when Akin runs out of money and some MO Republican can run a write-in campaign (or if he drops out soon enough, replace him as the GOP candidate). Hopefully for the GOP Akin runs out of money before October or the final month crunch or whatever you want to call it. Heavens know that they wouldn't be too pleased about losing some votes to a compromised candidate.
As for the chances now, not so sure. Whereas some more rational candidate would've performed better before, the GOP is still tainted. The fact that the GOP DID nominate a candidate like Akin, even if they changed their minds after a few weeks, has got to be on the minds of a few Missourians. This is like committing a grave offense to a person and then apologizing, expecting everything to suddenly be okay and them to totally forget what you did. Things can't just be thrown under a bus, kicked to the curb, dropped off at the Cleaners, or left
under the bridge. The GOP needs to do more than just nominate a "polite" politician, they need one with a new image. You can't keep Rachel Dawes and simply replace the actress, you need a Selina Kyle to keep things interesting.
As for blocking nutter candidates, where the hell was the RNC the past few election cycles?
EDIT: Yes, I did edit this post just to throw in a Batman analogy.