No.
I can think of good arguments for bicameralism and the idea of a longer tenured upper chamber.
I can't think of any good arguments for the Senate as presently constructed. The idea of giving tiny states' voters hugely disproportionate say does not make sense in a 50 state county. Arcane rules like the filibuster do not make sense. And, just historically, the US Senate has generally been an impediment to positive social change from the slavery debates to civil rights to regulating robber barons and industrial capitalism to the unconscionable obstructionism under Obama.
So, I would be fine abolishing it or drastically changing the rules and apportionment among the states.
Think about all the bills passed by the Republican-led House that the Senate has killed over the years.
This is a valid point to be made. The House tends to do lots of radical things, coming from both sides of the aisle. Having the Senate act as a brake on the actions of the House is useful in maintaining stability and moderation in our country.