If the Democrats put up another corporate/establishment/neoliberal candidate, Trump could use the same campaign strategy from 2016 (campaigning against free trade, which these type of Democrats endorsed) to win these states again.
This strategy gets knee-capped if Trump's escalating trade war with China sends the economy into a recession. Rural and small-town Midwest will be the hardest hit region by China's retaliatory tariffs.
Otherwise, yes, he could play this card again. I'm not sure it will be enough to keep PA, WI, and MI in his column, but it would be enough for OH and IA.
In relative terms, the trade war is much more damaging to IA's economy than the economies of MI/OH/PA/WI. Which may not be enough to flip the state, but it wouldn't surprise me if IA sees the biggest swing.