The US constitution can be amended for pretty much anything, including making us a dictatorship, which I assume is a sufficient (but not necessary) condition for anything including genocide. Actually, there is a logical flaw in the constitution that allows us to turn into a dictatorship, as pointed out by the greatest mathematician of modern times Goedel on his citizenship test (he was quickly shushed by his companion Einstein or his questioner depending on which version of the story you believe). Wikipedia has
one version of the story.
The exact mechanism of this logical flaw is unknown, though some think its just a matter of amending the constitution while others think its an inconsistency (in which case you can logically conclude anything you want).