Kennedy's loss, as noted above, means he is the first member of that family to ever lose an election in Massachusetts. And another thing-once his House term ends on January 3, 2021, it will be the first time in 74 years that no direct descendant of Joseph Kennedy Sr. will hold elected office anywhere in the United States. This doesn't count Amy Kennedy, Van Drew's opponent in New Jersey, who married into the family. Hopefully, the Kennedy dynasty will now find its way into the history books, like the Roosevelts and Tafts have.
I think there were a few weeks in the beginning of 2013 without a Kennedy but JKIII was representative elect then.