Are there any good candidates like state senators or reps in the area?
Brittany Pettersen (sitting state senator) and Andy Kerr (Pettersen's term-limited predecessor and current JeffCo county commission member), both from Lakewood, both announced they would run to replace Perlmutter when Perlmutter was planning on running for gov in 2018. Both have been working on the hill for several sessions and seem pretty well connected. Pettersen outran Polis in the district in 2018.
Tammy Story was also a pretty highly sought after State Senate recruit and was featured pretty prominently as a good investment for flipping the Senate in 2018.
The district isn't great for Ds but of course the state party outran Dems in most other states. It's a well-run party and the educated JeffCo (and growing DougCo) D voter bases will stay loyal and keep showing up to polls. This district in another state would make me sweat more but I have faith in the state party.
Interesting district to look into here is HD 25 which covers much of rural JeffCo. Ds flipped it in 2018 and held it by 3 points in 2020. There isn't really any suburb that tips into the district so it's pure D strength in exurbs (e.g. Evergreen) here.