Maybe. Based on Biden's performance, Democrats may have some room to grow in Charleston, Berkeley, Beaufort, Dorchester, Greenville, Richland and Lexington. And like in most of the Deep South, Republicans have probably maxed out with rural whites.
But the problem for them is that a lot of the population growth is from conservative retirees moving to Horry County. At least for the next couple cycles, these trends will probably cancel each other out and largely keep the state where it is.
Not to mention the conservative, evangelical influx into the Upland region.
