I'm not sure I agree with manned missions outside of LEO, because it doesn't seem very useful at the moment. However, I think we should significantly increase NASA's funding for R&D and other space-related investments.
Earth is set to undergo significant resource shortages for certain types of elements in the coming decades, and we need to prepare for this. Mining asteroids in space
(particularly the asteroid belt, between Mars and Jupiter). We will need much more advanced technology, especially in energy and robotics, to take advantage of these truly enormous amounts of resources.
That is where things are headed no matter what we do, so we should begin investing now so we can be prepared. So many discoveries will likely be made while developing the technology to do this and it will inevitably benefit mankind in ways that are hard to imagine, just like previous large R&D projects have.
No, and as long as there are still people who do not have healthcare, as long as there are people who cannot afford an education, the US should cut back on its expenses in space and invest in more important areas that, you know, actually affect people's lives.
I see what you're saying, and it's perfectly understandable, but NASA's budget is already far smaller than it used to be, save for the small bump it got recently, iirc.
However, as I was rambling on about above, we will need to begin taking advantage of the resources in space no matter what we do on Earth and it's best we focus more resources on speeding up the exploitation of those space-based resources. IMO that should be a primary objective for NASA & private industry, rather than symbolic manned missions.