Seriously though, I think the US and Russia should order a ceasefire in X days, and any parties not prepared to abide by such terms should be treated as enemies of the peace. That would include ISIS (obviously) but also any pro- and anti-Assad factions and groupings. From then on, play good cop, bad cop with Russia to oust Assad and give him exile, install a transitional leader in Syria from the current ruling party to prepare for elections in X years, send targeted drones after the leadership of factions still fighting in Iraq, prepare for an independent Kurd state and try to reform Iraqi governance under non-stupid means (i.e. no al-Malaki/Shia supremacists). In the long term, gather the leadership of Iran and Saudi Arabia and continually bash their heads together until they agree to wind down their childish feud; and generally blockade MENA dictatorships/rebel groups from arms imports.
no fly is basically garbage
Turkey, our main counterbalance to Russian influence in the Middle East, would really hate this idea.