I've always wondered why Eastern Tennessee has been so heavily Republican even during the Solid South days. Carpetbaggers perhaps?
Hillbillies are not plantation slaveholders.I think it goes beyond this, as plenty of hillbillies in the Deeper South were convinced that their economic well-being depended on a thriving South (and therefore thriving slave power). That argument didn't work in places like Northern Alabama, Eastern Tennessee, etc., as their economies weren't tied to slavery, and they (rightfully) felt totally betrayed by their states choosing to go to war with their country for the slave power's interests.