Republicans in Mississippi are far more inelastic than they are in either of those, regardless of the Presidential numbers.
In Congressional races, Mississippian Republicans have voted for good Democratic candidates over terrible Republican ones. It is not out of the question that (after 6 more years of favorable demographic drift), one of those same 2 Democrats who already beat a terrible Republican candidate in an overwhelmingly white Republican district could beat another terrible Republican candidate in a statewide race, when the state as a whole is less Republican that MS-1.
That was before there was a black guy in the White House.
For "Black guy in White House effect", see Arkansas.