Her health has visibly deteriorated rapidly since she lost her husband of seven decades last year.* She has lost a lot of weight, her colour isn't good and she can't manage public events longer than about an hour or so, even sitting down. It isn't entirely clear what the issue (or issues) are because The Palace is notoriously opaque about the health of senior Royals (last year they were insisting that Philip was fine, really, when it was extremely obvious that he was dying), but she's not a well old lady and people need to be realistic.
*This is a really common thing to happen, of course.
Yeah, though she akready outlived the timespan HW Bush had left after his wife of over 73 years died.
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