If I had to guess:
Chester PA
Fairfax VA
Loudoun VA
Prince William VA
DuPage IL
Lake IL
Forsyth GA
Collin TX
Tarrant TX
El Paso CO
Douglas CO
Orange CA
San Diego CA
I mean, the demographics of these counties from 2000-2004 and 2020 are drastically different. I might add Riverside and San Bernardino CA but they swung before Biden IIRC. There's also the county for Indianapolis which was red during Bush's time no?
Marion County, IN voted Republican in 2000 but went for Kerry in 2004. Mostly it’s because white middle class republicans moved out of places like Wayne and Pike townships and into Hamilton and Hendricks Counties.