Looking over state laws West Virginia seems like a strong candidate:
https://norml.org/laws/west-virginia-penalties-2/It has even a required minimum jail sentence for possession of any amount of 90 days. Now granted at the state level even "mandatory" minimums aren't as such in effect, they're often sentenced as probation or a suspended sentence, but that's well beyond most states.
There's also
this stupid yet kind of toothless federal law which requires states to suspend the driver's license of anyone caught with marijuana the same way it requires them to making the drinking age 21...well except that this offers an out in that the state can simply state that it's not complying without penalty and thus rendering the whole thing pointless. And thus 47 states have done so. The remaining three are Alabama, Arkansas and Florida, so those all would qualify as well.