Not really, when you look at how it was trending from 1996 onwards.
Also worth mentioning that McCain won by about 1/8 of one percent.
I think what's more interesting is that southern Missouri (and southern Kansas) didn't trend against the Democrats the same way that Oklahoma, Arkansas, and northern Texas did. Arkansas is an outlier in this era in politics for obvious reasons and Oklahoma is demographically distinct but this is still pretty fascinating, especially given how quickly D strength in Missouri continued to decline after 2008.
(2004-2008 swing)
