He would do well with rural whites and blacks, but Hillary would obliterate him with Hispanics.
2020 for Hispanics was more a positive reception of the Sanders campaign that year than a condemnation of Biden in particular. In this 2016, Hispanics would more likely be split to some degree between Clinton and Biden depending on what stances a Biden campaign took on issues affecting the communities and how much outreach it would do. I see Clinton more firmly rejecting the Obama administration in this scenario and maybe even pivoting to attacking Biden on the 2014 immigration crisis: she would certainly dominate with Cuban-Americans, but not necessarily Mexican-Americans. Or maybe Sanders would have an opening with the neoliberal wing potentially being tugged to the right.