To be completely honest, I wouldn't be surprised anymore to learn she won't run for reelection and pull a Jeff Flake. At least I think it's an underrated possibility.
I think this would be the best result for everybody. She spares herself humiliation by losing either the primary or general election, allows a new Democrat to take her place without a divisive primary occurring, and if they lose she can claim vindication that she could have beaten that Republican.
Now, personally, I want to see how Kelly does in 2022, or really how any statewide Democrat can do without Martha McSally being a presence, before I completely endorse her being primaried. I would still rather have her useless ass in the Senate than any Republican's reactionary ass.