He was toxic in New England.
Why so much more so than in 2016 though?
I saw someone mention that his hardcore confederate pandering (on things like the Condederate Flag and Condederate Base Names) might have had something to do with it because New England is basically the anti-South and proud of its Abolitionist and Civil War Union Heritage.
Definitely this, plus farming out social policy to the religious right while in office after campaigning in 2016 as more of a Scott Brownian culturally-conservative-but-not-socially-conservative candidate, something that does still play fairly well in much of the region. New Englanders are fine with a bit of immigrant-bashing and autarky but have very little time for Southern- and Lower Midwestern-style moral majoritarianism on drugs or sex.