If they're smart then a lot of these Democrats will never stop talking about these Republicans' ties to Trump. Very few of them are untainted by association with the current President, and if they can keep people fearful of Trump's Republican Party, then I think 2022 will be a much less painful midterm for Democrats than the Obama ones. There are no Blanche Lincolns or Mark Pryors or Mary Landrieus for Republicans to target in the Senate during the midterm. Hassan is the most vulnerable, but under the right circumstances, I could see Sinunu's campaign being somewhat of a repeat of Bredesen or perhaps more accurately (assuming he loses) Bullock, but that would only happen if Biden is moderately popular in the state and they nationalize these races.
It could also be a repeat of Bayh if Democrats remind voters who are fed up with a Democratic trifecta that Sununu greeted Trump on one of his rallies two years ago. That should be more than enough to trump the unfavorable environment, Sununu's popularity as the incumbent (not former) governor, an extremely energized Republican base, NH's far more competitive PVI compared to IN, and the barrage of attacks on Hassan pointing out that she cast the decisive vote for 95% of Biden's policies.
