Coleman Livingston Blease: EXTREME horrible person, literally supported lynching.
"Cotton Ed" Smith: Very slightly better than Blease but still an extremely awful, evil P.O.S
"Pitchfork Ben" Tillman: An evil, psychotic bastard. possibly worse than Blease, even.
Donald "Pee Wee" Gaskins: Obviously pure evil, but at least more endearing than the other options.
Angry Grandpa: the only person on this list who could be considered a FF. I miss him.
Strom Thurmond: Mega HP-turned more regular HP
John C. Calhoun: Possibly the worst VP ever, and looked like a serial killer too.
So yeah, overall, Angry Grandpa is clearly the only FF on this list. he was a decent man who wasn't a racist, murderer, or literal psychopath, so he takes the trophy of the "greatest" South Carolinian, I suppose