I mean, Iowa is still a swing-y state, especially in wave elections. Remember when Chet Culver lost by 10 in 2010? I have little doubt that Republicans are going to win this (and IA-01/IA-03) back in 2022.
If it's a Democratic midterm, sure, but if Trump is still president, there's a good chance Democrats hold all of those races.
I don't know who or when, but eventually we're going to get another president that doesn't instantly piss more than half the country off, and we'll get a more neutral midterm that isn't particularly exciting. What I do know is that the generation(s) largely driving this toxic political environment are dying off and the 2020s is exactly the time where they will be marginalized for the first time since they moved beyond where Millennials are now.
Point being that I think it's a uniquely bad time to try and forecast midterms 4 or more years from now, potentially under an administration from the current opposition. The only instance where I think it would be more than appropriate is under a 2nd-term Trump, given who we know the man to be
(and how set in his volatile ways he is), the nature of his presidency and the tendency for 6-year itches to be rather brutal, even for presidents who were actually somewhat popular during their first term.
