No matter if the Senate cannot pass a full repeal (with or without a replacement) -the drive to repudiate a key element of President Obama's legacy is strong enough that I think both House and Senate Republicans will succeed ultimately in overturning the law. Even just a 'skinny repeal' (which I think has more support among Senate Republicans than the other alternatives already voted upon, and therefore has a decent chance of becoming law) would jettison the individual and employer mandates that give health insurance companies an incentive to participate in the marketplaces. Coupled with Trump's pledge to wind down the subsidies, and the law would go down a true death spiral into oblivion:
http://www.politico.com/story/2017/07/26/obamacare-markets-skinny-repeal-241003