Do we think that Republicans are likely to draw Jim Cooper out of a seat following 2020? It is really easy to carve up Nashville given how Republican the surrounding districts are (and since Nashville is actually only moderately Democratic-leaning itself).
I don't know if I'd call 60-34 a moderately Democratic leaning county, but yes. We can probably assume that unless the Supreme Court rules partisan gerrymandering unconstitutional the Nashville, Louisville, and maybe Kansas City seats will be ripped apart.
Louisville cannot be gerrymandered, Anne Northup was the last stand there and Louisville got bluer and bluer until it voted out Anne Northup, Kansas City will make one of the Western MO seats competitive. Out of these, Nashville is probably the most feasible, but I don't think Republicans want to gerrymander Democratic cities and create dummymanders, as they did in NJ, VA, TX, and GA