The electoral college is an anti-democratic anachronism that needs scraped in favor of pure popular vote. While in theory the ME-NE system is slightly more democratic, in practice it's only purpose for nationwide implementation is to ensure Republicans win the electoral college even if they lose the popular vote by several million.
If someone is willing to build on Libertas's work to determine at what point in the national vote (assuming each CD vote tracked national changes) it would take McCain to win the EC, or Gore in 2000, you'll see my point quite vividly.
For Gore to win in 2000 under the Maine-Nebraska method, he would have needed to pick up 18 electoral votes. Assuming a uniform swing from Bush to Gore and no change in third party votes, these 18 votes would have been the first to flip:
FL (Statewide) (0.01% margin) 2 votes
VA-4 (0.20% margin) 1 vote
FL-8 (0.28% margin) 1 vote
MI-10 (0.53% margin) 1 vote
WA-3 (0.85% margin) 1 vote
PA-21 (0.90% margin) 1 vote
NH (Statewide) (1.27% margin) 2 votes
IA-3 (1.40% margin) 1 vote
AR-2 (1.42% margin) 1 vote
MN-1 (1.68% margin) 1 vote
MN-6 (1.97% margin) 1 vote
FL-7 (2.06% margin) 1 vote
IA-4 (2.08% margin) 1 vote
CA-44 (2.45% margin) 1 vote
AZ-5 (2.46% margin) 1 vote
OR-5 (2.47% margin) 1 vote