They probably liked the Compromise of 1850 as a slave state.
It had more to do with the nativism of the American Know-Nothing Party. Michael F. Holt's The Rise and Fall of the American Whig Party: Jacksonian Politics and the Onset of the Civil War, is perhaps the best source state by state in terms of breaking down how each state transition from the Second to the Third Party Systems.
When the ex Whigs embraced the Know-Nothings in the 1850s as a vehicle for their hopes, it forced a massive realignment in both Maryland and Louisiana.
Prior to the mid 1850s, Whigs had tended to do well with well off Catholic Plantation Owners, while the Democrats did well with the small white farmers and workers in Baltimore, especially the Protestant ones. Once the Whigs embraced nativism, this reversed and Democrats began to dominate the Catholic Plantation owners while now Know Nothing ex Whigs had the far more numerous small farmers and workers flip over to them.
