I don't know.
I think Hillary might have had a hard time somewhat, simply because Republicans have an unnatural and undefined hatred of her, but I do believe she would've been more effective as president than Trump. She knows Washington, she can actually form a coherent sentence, and even with all the scandals in her closet she is actually a patriot (that is, she wouldn't sell the country out to a foreign power). Clinton, for all her many faults (and there are many), would still work to better the country and its people. Trump works for Trump to better Trump and his brand; he has no care for the country, or its people. He only serves himself and his desires; everything else is unimportant.
Better? Yes. Good? Probably not. I anticipated a Bush 41 Presidency from her and honestly the Democrats dodged a bullet with her loss. The 2018 midterms would've been much worse and a Republican President would've won in 2020 with a much stronger Republican Congress. The fact that Trump is the era's Republican President instead of a much better tactician like John Kasich has helped Democrats enormously.
But returning to Hillary, the Republican House would continue to not take ownership of ACA. They would've probably made the Medicare issue a major crisis in 2018. The foreign situation and recession would've tripped up Hillary too. additionally the Democrats are not the majority coalition so ...
The problem is that this time period presents major problems that neither political coalition is equipped to handle. The technocratic minority Democratic coalition or the ruling neoliberal socially evangelical Republican coalition are now facing issues that threaten their reason for existing.