I think you guys are forgetting that WV is one of the most Democrat states in the entire country.
The Democrats focused on a different path toward an electoral victory which was mainly Ohio and let WV go.
These can't go unchallenged. West Virginia is heavily Democratic on the local and state levels, however that hasn't carried over in recent elections at all. I would not be surprised at all in Manchin takes 64% again and the Republicans narrowly carry the state.
As for the second statement, the claim that the Democrats gave up on Ohio is preposterous. That was the campaign's focal point for both sides.
As for the question it depends on who the nominees are. In West Virginia, Huckabee is favored over everyone but Edwards, Edwards is favored over everybody, Romney and Giuliani are almost dead on arrival. Clinton should do well, etc. In Colorado, Obama and Clinton are favored over the Republicans except Giuliani. I'd say Colorado