It doesn't translate much into political support in the Democratic Party, which is surprising. I could see a Democratic congressional candidate from a district with a substantial Muslim population trying to win support on that issue by promising to be a voice for Palestine in congress.
Even if you gerrymandered the hell out of the Dearborn, MI area, you still wouldn't have a substantially Muslim district in the way that some legislative constituencies in Western European countries are 30%+ Muslim.
The only people in Congress who occasionally thumb their noses at AIPAC do so less out of an organized pro-Palestinian position and more because they have little need to appeal to pro-Israel donors/lobbyists. The usual suspects tend to be non-Muslim Arab-American legislators (Nick Rahall; Justin Amash - though his foreign policy views are as much informed by his Paulist Republicanism) or members from mostly rural, homogenous districts with no politically active Jewish community.