West Virginia would go heavily for Obama (look at his numbers in Southern IL...)
Look at his numbers everywhere, WV would vote for Keyes, rather than a very liberal Obama. Turnout may be below 40% though.
IIRC his numbers in Southern Illinois (by that I don't just mean Downstate Illnois, btw) were particulary good.
Besides people like Keyes have never played well in most of WV (he'd do well in Grant county though...) and a candidate being liberal in WV isn't a serious drawback if they talk the right language on economics and don't piss off the local party bosses.