Interesting that the Tories still represent the two rich downtown neighborhoods (Kensington and the City). In the US, those would be the most uppity of Democrat districts--think Henry Waxman's Westwood or Carolyn Maloney's Upper East Side.
Cities of London & Westminister (or is it the other way round?) possibly (although the more politically "downtown" seat is Regents Park & North Kensington, a safe Labour seat nowadays), but
not Kensignton & Chelsea (you don't really get anywhere like it in the U.S nowadays...)
North Southwark & Bermondsey (then called Bermondsey) was a Labour stronghold until a vicious by-election in the '80's when Simon Hughes (Lib) won it... he's made it his personal fiefdom and wins on the back of a huge personal vote (although he nearly went down in '97)