God actually calls constellations by name in His rebuke of Job. "Canst thou bind the sweet influences of Pleiades, or loose the bands of Orion? Canst thou bring forth Mazzaroth in his season? or canst thou guide Arcturus with his sons?"
Did he actually say Pleiades and Orion in the Hebrew version, or is this just how it was translated into English so that people reading an English Bible would understand what the heck God was saying? I'm quite sure that Moses and his people would refer to them as something else.
Well, some people think that. Others aren't sure.
http://en.wikipedia.org/wiki/MazzarothMore importantly, how do you know that this interpretation of the Zodiac as telling some kind of story relevant to the Christian God is even accurate? How do you know that the zodiac weren't some other religion's thing and some people who would like it to fit into their own haven't co-opted it for the Christian religion? I mean, if these zodiac constellations were important symbols to Christianity don't you think there would be a more explicit mention of that in the Bible?
Also, being the astronomy buff that you are, you are no doubt aware that the stars are actually moving and that in time the positions of the stars that make up these constellations will change relative to one another and so what we see will also change, right? If these zodiac are meant to be some kind of gospel sign, why would they change?
http://news.discovery.com/space/changing-constellations-50000-years.html