Does Federal Law trump state constitutions?

[beneficii]

A friend and I were discussing this, in reference to health care, and I couldn't remember a specific example that would definitively answer this for me.  I feel like this is something I should know, but I honestly can't remember.

Yes.

You must be logged in to read this quote.

(emphasis added)

U.S. Const., Art. VI

[beneficii]

Normally the Supremacy Clause would say yes, but not if the law in question is unconstitutional which is why such a large number of states are preparing to to challange the Health Care Bill in federal court.

That is correct, because the clause says, "This Constitution, and the Laws of the United States which shall be made in Pursuance thereof; ..." (emphasis added).