Is New England and the South voting opposite each other explained by slavery and the Civil War?

[All Along The Watchtower]

Much more abolitionist than average New England vs. the Southern Slave Power, the former being extremely Unionist against the latter literally being the Confederacy.

I’d argue that the specific political parties the two regions happen to be dominated by at any given point in history aren’t nearly as important as the consistent pattern of the two regions being polarized against one another politically.