As far as presidential elections go, they've given up on 2012 and are focusing on 2016. They are probably going to place more resources on down-ballot races this year instead.
They have much to defend and little to gain. The Tea Party zealots and stealth candidates of 2010 have shown what they are: achievers of discord who have shown no relevance to the American future examples of how not to do politics. The best thing for the GOP in 2012 would be an electoral massacre that forces Republicans to redefine themselves.