It's more likely Capito runs for re-election than challenges Manchin. If she wanted to run for the Senate, she would've done it this year, when the Republicans pulled out the chair for her.
She didn't think Manchin could be beaten, so she didn't want to run. Now that we know that Manchin could have been beaten, she may be more likely to run. Hard to guess at the moment, but she does have aspiration beyond the House.
Except for the fact that it's unlikely to find such a set of favorable circumstances as this year.
Not to mention that West Virginia seems very fond of its incumbents.