Could this be the beginning of the end?
As has been demonstrated time and time again, the answer to that question is always "no." People really ought to stop asking it.
National polling trends put "the beginning of Trump's end" back sometime around the start of March. It doesn't really matter how the R nomination contest goes for him if he can't turn that around. (And no, I don't think he can.)
That's the beginning of the organized anti-Trump effort. You really need to start reading these national polls in the context of the current stage of the race (i.e. contested Pub primary), which means that a lot of Pubs are against Trump. They will come home by November, like the PUMAs.