1. She hasn't been vetted. We'll see what things might turn up for her.
2. She hasn't spoken on the national stage. How will can she speak before thousands?
3. She hasn't debated on the national stage. Can she hold her own against and beat down Mike Pence in a national debate?
Yes. I think Cortez Masto would be a strong pick but she has NOT been put under the media spotlight of a presidential campaign. One major reason Biden is looking at Harris and Klobuchar so closely is because they have already undergone vetting by the national media and shown they can handle speaking in front of a national audience during their own presidential campaigns. Biden himself was a failed 2008 presidential candidate before becoming VP.
We have not seen Cortez Masto's dirty laundry. But that doesn't mean there is none.