Hillary should receive at least half of the popular vote. She will receive a minimum of 290 EV's and a maximum of 347. I hope she picks either Gov. Cuomo, Sen. Kaine, or Gov. Bill Richardson as her running mate. Hillary 2016!
Cuomo would be a disaster. Richardson is a decent choice if Hillary isn't holding a grudge.
She'll pick a loyalist from 2008. The Clintons are all about loyalty.
My bet is on one of the Castro brothers from Texas, although (obviously) I would prefer Ed Rendell (but I know he would make a great campaign manager as well).