I certainly think there's a chance it could happen, especially if Trump loses but Democrats fail to take the Senate in 2020. Republicans clearly have a major advantage with the Senate map, and I expect Democrats to generally control the presidency (meaning less Dem-friendly midterms).
Democrats had a lock on the House for 40 years (1955-1995), so it's not like there's no precedent.
But not the senate. I think Republicans were able to hold the Senate for 16 years at one point and the Democrats 26 years? It's truly a dynasty if the GOP is still in control in 2024.