This thread is very clearly about federal/presidential politics given the board, though, so all you're saying about DuPage/Lake voting massively to the right of the state in gubernatorial elections doesn't hold much relevance here. Obviously, local politics are prone to producing divergences from the federal level, but you can't really compare the performance of someone like Bruce Rauner to a federal Republican.
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To answer the question, I think a federal Democrat is guaranteed to win Champaign and Lake in addition to Cook at the bare minimum in the foreseeable future.