Colorado and North Carolina are clearly the most promising. I wouldn't call Gardner DOA but he's awfully close, while Tillis is a terrible incumbent in a state with a good Dem bench.
Other potential pickups:
* Alaska: Begich stupidly deciding to run for governor kinda made this harder for Dems
* Georgia: Perdue has gone full nativist in a state getting more diverse by the minute
* Iowa: Ernst is a good candidate, but not invincible
* Kentucky: The Bluegrass State is stily fairly, uhm, blue downballot — and lord knows if Cocaine Mitch will run again
* Maine: I don't buy that Collins is safe; she's done a fantastic job at pissing off both party's bases
* South Carolina: Longshot, but if Lindsey Graham loses a primary to a nutjob then things could get interesting
* Texas: Ask me again after November
* West Virginia: Senator Richard Ojeda?
Of course, a lot of these are stretches. But if 2020 is a wave year, then this Senate class has the potential to be a disaster for the GOP.
Can't ignore Montana if Bullock runs for Senate.