Which incumbents, if any, are vulnerable to losing a primary challenge? Jim Cooper’s challenger might be irrelevant if TN-05 is cracked.
Good question.
On the GOP side:
Cheney
Gonzalez
Kinzinger
Mooney (though he's unlikely to be an effective incumbent)
Palazzo
Rice
Upton (surprised nobody else has mentioned him)
On the Dem side:
Auchincloss
Cooper
Cuellar
Foster (surprised nobody else has mentioned him)
Carolyn Maloney
Scott (GA)
Schrader
I would also say Gomez has a fair chance of losing in the general to another D based on the 2020 results though I don't know the local circumstances.
Not sure about Fletcher but as you say it's plausible. The same would apply to Newman.