Against a named candidate I would predict Flake would be down 4-6 points in this poll. The approval numbers probably aren't accurate but if they are (and are being replicated in internals for other orgs/candidates/etc) Flake could well lose the primary.
Basically this. In no way would he be down 16 to Sinema, but probably more like 5 or so. AKA--he's doing worse than McCaskill. But MUH Trump states and MUH Democratic obstructionism
I could certainly see the national environment shaping up in a way that produces a McCaskill reelection happening in conjunction with a Flake defeat, though I believe McCaskill's issue is increasing Dem turnout whereas Flake's is managing his image.